Sanofi – Big Data and Translational Medicine
Presentation by David Peyruc and David Erwan
third largest Pharma company
Invest 4.7B Euros per year. From revenue of 33.4B Euros.
The challenge for Pharma
The classic business model is under threat. Generic drugs are a threat – “The Patent Cliff”
End of the Blockbuster Age.
Translational Medicine is about bridging the gap between Clinical and Research worlds. Linking Hypothesis with Evidence.
Genomics and other *omics data needs to merge with other data. (See my other post from the Broad Institute from yesterday).
Translational Medicine Challenges
- Diversity of data objects.
- Large storage requirements. Genomics data is big.
- Consistency and Traceability
- User Friendly curation process for annotation to enable understanding and extract knowledge
Big Data (MongoDB) is used to help Extract, Curate, Normalize and Load data.
MongoDB is the central repository for Biomarker data.
- File and Metadata together.
- Scalable (Data was sharded from day 1)
- Easy to instal, use,understand and adapt/adopt.
The Journey to MongoDB
- Big Data White Paper
- Install and Benchmark
– Runnong GridFS
– Apache Solr for search access
– Collections of Metadata, Config, User profile, Logs, tools etc.
- Implement a REST API service layer
- Build a web, Desktop and third party software integration interface (using Rest API)
360 degree Explorer
- Disease or Syndrome / Receptor
Geographic Zone / Health Activity
- Show the same data via faceted navigation
The platform is not a standard IT product. So there is minimal IT support.
- More efficient tagging and curation
- Awareness of more data sources
- Easy exploration of data
- Easier integration of external data
- Faster development
- Documentation, support, training and community support.
Twitter connections for the presenters.
[tag health cloud BigData MongoDB MongoDBWorld NoSQL]
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Disclosure: I began as a Patient Engagement Advisor and am now CTO to Personiform, Inc. and their Medyear.com platform. Medyear is a powerful free tool that helps you collect, organize and securely share health information, however you want. Manage your own health records today. Medyear: The Power Grid for your Health.